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Ingcaciso yeMveliso

I-peony glycosides emhlophe yimonoterpene glycoside etsalwe kwiingcambu zePaeonia lactiflora, ebonwa njengeyona nto isebenzayo yamayeza esintu amaTshayina "Ingcambu yePeony emhlophe" eneziphumo ezibonisa ukulwa- nokudumba, ukuthomalalisa iintlungu, kunye ne-neuroprotective. Isebenzisa itekhnoloji yokucoca i-high-yesantya esiphezulu-ikhromatografi yangoku (HSCCC), imveliso yethu ifezekisa impumelelo eyi-99.5% ye-ultra{5}}yokucoceka okuphezulu nge-5× eyongeziweyo yokufumaneka kwezinto eziphilayo xa kuthelekiswa nezicatshulwa eziqhelekileyo. Idweliswe njengomgangatho wereferensi kwi-Pharmacopoeia yaseTshayina ngo-2020.

Iimpawu zeMveliso

Ipharamitha	Iinkcukacha
Umthombo	Iingcambu ezomileyo zeI-Paeonia lactifloraPall. (Ranunculaceae)
Imbonakalo	Mhlophe ukuya -mhlophe crystalline umgubo
Ubunyulu	Enkulu kune okanye ilingana nama-98% (HPLC)
Ifomula yeemolekyuli	C₂₃H₂₈O₁₁
Ubunzima beMolekyuli	480.47
Ukunyibilika	Inyibilika ngokukhululekileyo kwimethanol/ethanol, inyibilika kancinane emanzini (1g/100mL, 25 degree)
Iziqinisekiso	ISO22000, HACCP, USDA Organic, Halal

Uhlalutyo lweNdlela yoBugcisa

Icandelo	Umxholo/iipropati	Iingenelo
I-Paeoniflorin	Enkulu kuno okanye ilingana ne 98% (HPLC-ELSD)	NF-κB inhibition yendlela (30% isebenza ngakumbi kunedexamethasone)
Albiflorin	Ngaphantsi okanye ilingana ne-1.0%	I-Synergistically iphucula umsebenzi we-GABA receptor (i-anxiolytic)
Iintsimbi ezinzima	Pb Ngaphantsi okanye ilingana no 0.5ppm	Ithobelana ne-ICH Q3D yezikhokelo zokungcola okusisiseko
Iintsalela zokunyibilikisa	I-Methanol Ngaphantsi okanye ilingana no-200ppm	Ihlangabezana neemfuno ze-EP pharmacopeia

Iiparamitha eziphambili:

Indawo yokunyibilika: 196-198℃(ukubola)

Ukujikeleziswa okuthe ngqo: [ ]D²⁰=-12.5 isidanga (c=1, kwimethanol)

Ilahleko ekomisweni: Ngaphantsi okanye ilingana ne-1.0%

Usetyenziso

▍ Amayeza

Anti{0}}Izitofu zeArthritis: Idityaniswe ne-methotrexate (ityhefu encitshisiweyo)

Neuroprotectants: Amalungiselelo e-Ischemic stroke IV (ulingo lweSigaba sesi-III)

▍ IiNutraceuticals

Ukukhuselwa kwesibindi: Ukunciphisa amanqanaba e-ALT / AST (i-40% iyancipha kwizilingo zeklinikhi)

Anti-Ixhala Gummies: Ukukhutshwa ngokukhawuleza -(imizuzu eyi-15 iqala)

▍ Izithambiso

Ukulungiswa kolusu olubuthathaka: I-TRPV1 inhibition ye-receptor (72%↓ imvakalelo evuthayo)

UAnti{0}}IiSerum zokuNyeka kweNwele: Yandisa isigaba se-anagen (35%↑ ingxinano yeenwele kwi-vivo)

▍ Unyango Lwezilwanyana

Canine Epilepsy Adjunct: Yehlisa umthamo we-phenobarbital nge-30%

▍ Amaziko ophando

Izifundo zeNdlela yeTLR4: Umgangatho wovavanyo lweseli (CAS 23180-57-6)

Ukupakisha kunye noGcino

Ukupakisha: 1kg / ibhegi yefoil, 25kg / idrum yefayibha (inokwenziwa ngokwezifiso)
Ukugcina: Gcina kwindawo epholileyo, eyomileyo, evaliweyo kwaye ikhuselwe ekukhanyeni
Ubomi beShelf: iinyanga ezingama-24 (phantsi kweemeko ezingavulwanga)

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