Iimfihlo zoKhuseleko lweDigestive zeMagnolia Extract
Ithathwe kwixolo lesityalo saseTshayina iMagnolia officinalis, uphando lwangoku lubonisa ukuba iqulethe iikhompawundi ezizodwa ezifanamagnololkwayei-honokiol. Asebenza njani la malungu ukuze abe ngabagcini bendalo benkqubo yokwetyisa?
Kuchazwa iindlela ezintathu ezingundoqo
Kutheni ikhulula i-spasms yesisu?
Yenza i-GABA-i-B receptors inqanda ukucutheka okugqithisileyo kwamathumbu agudileyo amathumbu (i-75% yezinga lokukhululeka kwe-spasm ebonwe ngekliniki)
Iibhloko iziteshi ze-calcium ukunciphisa ukunyanzeliswa kwamathumbu emathunjini (i-60% iyancipha kwi-contraction amplitude in vitro)
Ilwa njani nezilonda?
Inqanda ukukhutshwa kwe-asidi yesisu: Yehlisa i-H+/K{1}}Umsebenzi we-ATPase (45% inhibition yepompo yeproton)
Ukwandisa ukukhuselwa kwe-mucosal yesisu: Ivuselela i-prostaglandin E2 secretion (i-3-5 fold ukwanda)
UAnti{0}}H. Isenzo sepylori: Iphazamisa iibhaktiriya zebhaktiriya (izinga le-82% lokuphelisa)
Yintoni eyenza ukuba ilawule i-gut microbiota?
Ikhuthaza ukukhula kwe-bifidobacteria (ukuphindaphinda oku-2-3)
Inqanda iintsholongwane ezifana ne-C. difficile (i-15-18mm yendawo yothintelo yedayamitha)
IziNzuzo ezine eziQinisekisiweyo ngokwezonyango
Dyspepsia esebenzayo
I-68% yokunciphisa ukugcwala kwe-epigastric
I-72% yokuphucula ukuhlutha kwangoko
Irritable Bowel Syndrome (IBS)
I-55% iyancipha kwiintlungu zesisu esiswini
I-60% yokuphucula kwisigxina samathumbu
Unyango lweSilonda seGastric
I-40% ngokukhawuleza ukuphulukiswa kwesilonda
I-50% iphantsi izinga lokuphindaphinda
I-Antibiotic{0}}Isihudo esiNxulumeneyo
I-65% yokunciphisa izehlo
I-50% yexesha elifutshane lokubuyisela i-gut microbiota
Isikhokelo soKhetho lwezeNzululwazi ngokuqulunqa
|
Imeko |
Ifomu ecetyiswayo |
Ukugxila Okusebenzayo |
Umthamo |
Ikhosi |
|
Iintlungu zeGastric ezibuhlungu |
Khawuleza{0}}khulula iiCapsules |
30% magnolol |
200mg njengoko kufuneka |
I-PRN |
|
Ummiselo ongapheliyo |
I-Enteric{0}}icwecwe zeCwecwe |
20% honokiol |
100mg TID |
Iiveki ezi-4-8 |
|
Dysbiosis emathunjini |
Iprobiotic Complex |
5% magnolol + probiotics |
1 ipakethi yonke imihla |
Iiveki ezili-12 |
ImiQathango engundoqo yokusetyenziswa
⚠ Ngubani ofanele alumke?
Abasetyhini abakhulelweyo (banokuchaphazela isihlunu esigudileyo sesibeleko)
Izigulana ezine-Hypotensive (uxinzelelo lwegazi oluphakathi{0}}isiphumo sokwehlisa)
⚠ Izilumkiso zokuSebenza kweziyobisi
Yenza i-sedatives (uhlengahlengiso lwedosi luyafuneka)
Inokuchaphazela i-anticoagulants (monitor INR)
Imigangatho emithathu yeGolide yoMgangatho
① Iyonke i-magnolol+honokiol Inkulu kuno okanye ilingana ne-25% (iqinisekisiwe i-HPLC)
② Ixolo -elithathiweyo (5-8× lisebenza ngakumbi kunesicatshulwa samagqabi)
③ Idibana nemida ye-pharmacopoeia microbial (CFU<100/g)
Iingqinisiso zabasebenzisi
"Iminyaka yam yokuqunjelwa kwe-IBS iphucuke kakhulu emva kweeveki ezi-2" - 32umsebenzi waseofisini
"Isantya sokuphola kwesilonda sam sothusa nakwigastroenterologist yam" - 45yenkosi
Ukuqhubela phambili koPhando ngoomatshini
Amathumbu{0}UkuModareyitha kwe-Brain Axis(Izinto ezintsha ezifunyenweyo)
Ichaphazela i-CNS nge-vagus nerve
Yehlisa i-visceral hypersensitivity (i-35% ephezulu yeentlungu zentlungu)
Gut Barier Ukulungisa(Izifundo zezilwanyana)
I-2 × ukwanda kweprotheyini ye-tight junction ZO-1
I-40% yokunciphisa amanqanaba e-serum endotoxin
Yintoni eyenza i-Magnolia Extract ihluke?
Xa kuthelekiswa -namachiza eGI ekujoliswe kuwo, isicatshulwa semagnolia sisebenza ngale:
Multi-intsebenziswano yamacandelo (magnolol + honokiol)
Multi-intshukumo yenkqubo (imithambo-luvo + izihlunu ezigudileyo + i-microbiota)
Ummiselo we-Bidirectional (ibhalansi hyper/hypo{0}}umsebenzi)
